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Slither
I enjoyed it. It did a fine job of mixing horror with humor. The humor didn't spoil the horror and the horror didn't overpower the humor. On that note, Nathan Fillion may be the new King at mixing genres. His sci-fi/humor approach was right on as Captain Mal Reynolds in Serenity and his take on horror/humor was dead on the money again as Police Chief Bill Pardy in Slither.
The other two leads were very good also. Elizabeth Banks as the wife of...well, it's a demanding role, trust me on this. And BTW, Banks is one hot surburban momma. In junior high, this is what I wanted all my teachers to look like. She's not Pam Anderson hot, she's more of a Naomi Watts Perfect Woman Next Door hot. And of course, Chief Pardy has the hots for her.
The other lead is Michael Rooker as Banks' husband. He's good too. This is just a fun, sometimes funny, sometimes genuinely scary movie. I jumped in my seat twice that I can remember. I always hope the people behind don't see that. ;-)
As for "zombies, critters running amok, alien mutants taking over the world" movies; this ranks right up there. There's good action, there's good dialogue delivered by actors who are fun to watch, there's ample gore and grossness and it's a pretty decent story.
Probably the best of its kind I've seen since Tremors.
B+ ...for the fun of it
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My name is Maximus Decimus Meridius, commander of the Armies of the North, General of the Felix Legions, loyal servant to the true emperor, Marcus Aurelius. Father to a murdered son, husband to a murdered wife. And I will have my vengeance, in this life or the next.