Grace will join Tobey Maguire, Kirsten Dunst, James Franco, and Thomas Haden Church in the blockbuster franchise.
Spider-Man 3 is scheduled for release on May 4, 2007, and will reunite returning cast members with director Sam Raimi and producers Ziskin and Arad, the successful filmmaking team responsible for the first two films.
The "Spider-Man" film franchise has grossed more than $1.5 billion in worldwide ticket sales to date. Production on Spider-Man 3, which was written by Alvin Sargent, is scheduled to begin early next year.
"I couldn't be more excited about the direction we are taking the continuing adventures of Peter Parker," said Raimi. "Topher Grace is an extraordinarily talented actor and will be perfect for the complexities of the role we are developing."
While speculation continues about which characters will be called into action, the studio will not comment on the new roles beyond confirming the casting of Grace and Church.
Spider-Man 3 is being overseen by Columbia's President of Production Matt Tolmach and Shannon Gaulding, Director of Development for the studio.
Source: Coming Soon