I can't find it now, but there's a clip of him shrieking on the phone where he busts out some incredibly high pitched voice. It's hysterical. He's a great actor, and I don't think it's much of a mark against a great actor to say that they can't scream and shriek and flip out, but he can't.
This is the exact scene and line I was thinking off when I mentioned it! He yells his wife's name into the phone, and the look on his face and the delivery had me cracking the frak up.
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“It takes considerable knowledge just to realize the extent of your own ignorance.” ― Thomas Sowell