13 TV Marriages that Killed the Show:
1. Tony and Jeanne, I Dream of Jeannie
2. Rhoda and Joe, Rhoda
3. Jack and Vicky, Three's Company
4. Mike and Kate, Growing Pains
5. Charlene and Bill, Designing Women
6. Phillip and Maggie, Different Strokes
7. Niles and Daphne, Frasier
8. Booth and Bones, Bones
9. Mork and Mindy
10. Man About the House
(Although it did immediately trigger two spin offs, George & Mildred and Robin's Nest)
1. Tony and Jeanne, I Dream of Jeannie
2. Rhoda and Joe, Rhoda
3. Jack and Vicky, Three's Company
4. Mike and Kate, Growing Pains
5. Charlene and Bill, Designing Women
6. Phillip and Maggie, Different Strokes
7. Niles and Daphne, Frasier
8. Booth and Bones, Bones
9. Mork and Mindy
10. Man About the House
(Although it did immediately trigger two spin offs, George & Mildred and Robin's Nest)