As for some other thrillers from the 21st Century that I'd recommend if you liked
Prisoners, first some obvious ones...
David Fincher's
Gone Girl,
Panic Room,
Zodiac, and
The Girl with the Dragon Tattoo. Fincher is one of the very best filmmakers around, and his slick visual style and delight in working in genre make him an obvious choice. Christopher Nolan's
Memento, if for some reason you've never seen that. It put Nolan on the map, pre-Batman, and while some may find it gimmicky it is a very engaging gimmick and a heck of a ride. Joel & Ethan Coen's Oscar-winner
No Country for Old Men is a must-see. And certainly the very cinematic HBO series
"True Detective" you should see, ASAP, if not sooner. Most everybody was violently split on whether the second season worked at all, but the praise for the first season starring Matthew McConaughey and Woody Harrelson is unanimous.
As for a few that will be well known to many members here but have much less visibility in the mainstream, and while thinking about McConaughey, I'd recommend Bill Paxton's creepy and effective
Frailty (2001), which should satisfy both your horror and your suspense cravings. Jake Gyllenhaal is magnificent in Dan Gilroy's
Nightcrawler, which is ominous and suspenseful and a terrific character study of a deeply amoral creep. Jeremy Saulnier's
Blue Ruin is a terrific, gritty throwback revenge Noir that was a sensation on the Indie circuit last year, but it needs to be discovered by more people. Guillaume Canet's
Tell No One is a modern French Hitchcockian thriller about a man trying to unravel the mystery of his wife's murder. And the South Korean flick Hong-jin Na's
The Chaser is bloody enough it probably owes more to Brian DePalma's best work than a direct line to Hitchcock, but the intense game of cat and mouse may be exactly what you are looking for.
That should keep you busy for a few days, anyway.