The Shoutbox
"Happy Festivus, Georgie."
"Hand me a shtickel of fluoride."
"Yay! Jerry got it open!"
"Pimple popper M.D.!"
"Bad chicken...mess you up!"
"You're an anti-dentite."
Easily one of the best lines in sitcom history -- at least what I've seen of it.

"In this tiny apartment?"
"And you want to be my latex salseman."
"I drive them to lesbianism. And he brings 'em back..."
"Who told you to put the cheese on? Did I tell you to the put the cheese on? You people with the cheese...it never ends."

Jackie Chiles...easily one of my favorites.

"Mr. Marbles?!"
"I'm not a lesbian. I hate men, but I'm not a lesbian."